Paul T Schumacker Selected Research

myxothiazol

10/2006	Increases in mitochondrial reactive oxygen species trigger hypoxia-induced calcium responses in pulmonary artery smooth muscle cells.
10/2002	Mitochondrial reactive oxygen species trigger calcium increases during hypoxia in pulmonary arterial myocytes.
6/2002	Mitochondrial ROS initiate phosphorylation of p38 MAP kinase during hypoxia in cardiomyocytes.

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Paul T Schumacker Research Topics

Disease

37	Hypoxia (Hypoxemia) 01/2018 - 03/2002
9	Pulmonary Hypertension 09/2015 - 02/2008
9	Neoplasms (Cancer) 02/2015 - 09/2006
8	Hyperoxia 08/2015 - 02/2008
7	Ischemia 04/2013 - 03/2002
5	Parkinson Disease (Parkinson's Disease) 11/2021 - 12/2010
3	Mitochondrial Diseases (Mitochondrial Disease) 01/2019 - 06/2005
3	Lung Injury 08/2015 - 04/2011
2	Diabetic Nephropathies (Diabetic Nephropathy) 11/2017 - 01/2016
2	Fibrosis (Cirrhosis) 01/2015 - 04/2011
2	Vascular Remodeling 02/2014 - 05/2013
2	Lymphoma (Lymphomas) 01/2013 - 05/2008
2	Reperfusion Injury 06/2007 - 01/2003
1	Parkinsonian Disorders (Parkinsonism) 11/2021
1	Chronic Obstructive Pulmonary Disease (COPD) 01/2021
1	Heart Rupture 01/2019
1	Sickle Cell Anemia (Hemoglobin S Disease) 01/2018
1	Iron Deficiencies 01/2018
1	Polycythemia (Erythrocytosis) 01/2018
1	Heart Diseases (Heart Disease) 01/2017
1	Bronchopulmonary Dysplasia 08/2015
1	Pulmonary Fibrosis (Fibrosing Alveolitis) 01/2015
1	Asbestosis 01/2015
1	Wounds and Injuries (Trauma) 06/2014
1	Right Ventricular Hypertrophy 12/2013
1	Left Ventricular Hypertrophy (Ventricular Hypertrophy, Left) 12/2013
1	Inflammation (Inflammations) 08/2013
1	Rupture 04/2013
1	Neoplasm Metastasis (Metastasis) 01/2013

Drug/Important Bio-Agent (IBA)

33	Reactive Oxygen Species (Oxygen Radicals)IBA 11/2017 - 03/2002
18	Oxidants (Oxidizing Agents)IBA 10/2017 - 04/2002
15	Proteins (Proteins, Gene)FDA Link 01/2018 - 06/2007
13	AntioxidantsIBA 08/2015 - 06/2002
11	Oxygen (Dioxygen)IBA 01/2017 - 01/2003
8	CalciumIBA 01/2017 - 10/2002
7	Electron Transport Complex III (Coenzyme Q-Cytochrome-c Reductase)IBA 01/2018 - 03/2002
6	CatalaseIBA 08/2012 - 10/2002
5	Superoxides (Superoxide)IBA 10/2017 - 06/2002
5	Phosphotransferases (Kinase)IBA 09/2011 - 06/2002
4	NADPH Oxidases (NAD(P)H oxidase)IBA 10/2017 - 04/2002
4	Mitochondrial DNA (mtDNA)IBA 01/2015 - 09/2007
4	Transcription Factors (Transcription Factor)IBA 11/2013 - 09/2006
4	Superoxide DismutaseIBA 08/2012 - 10/2006
3	Messenger RNA (mRNA)IBA 01/2018 - 04/2002
3	EnzymesIBA 08/2015 - 09/2007
3	Sirtuin 3IBA 12/2013 - 01/2010
3	Adenosine Triphosphate (ATP)IBA 04/2013 - 02/2007
3	Adenosine Triphosphatases (ATPase)IBA 11/2011 - 02/2007
3	myxothiazolIBA 10/2006 - 06/2002
2	Protein Isoforms (Isoforms)IBA 01/2018 - 05/2013
2	Protein Kinases (Protein Kinase)IBA 01/2018 - 11/2011
2	Dynamins (Dynamin)IBA 01/2016 - 02/2012
2	Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric 05/2013 - 09/2011
2	Mitochondrial Permeability Transition PoreIBA 04/2013 - 04/2011
2	Sulfhydryl Compounds (Thiols)IBA 08/2012 - 06/2007
2	Type 5 Cyclic Nucleotide PhosphodiesterasesIBA 08/2012 - 02/2008
2	Adenosine Monophosphate (AMP)IBA 11/2011 - 09/2011
2	Small Interfering RNA (siRNA)IBA 09/2011 - 03/2009
2	Green Fluorescent ProteinsIBA 09/2011 - 06/2007
2	Cytochromes c (Cytochrome c)IBA 07/2011 - 06/2005
2	Cysteine (L-Cysteine)FDA Link 02/2008 - 06/2002
2	Rieske iron-sulfur proteinIBA 09/2007 - 06/2005
2	Cyanides (Isocyanides)IBA 10/2006 - 10/2002
2	Antimycin AIBA 10/2002 - 03/2002
2	RotenoneIBA 10/2002 - 04/2002
2	diphenyleneiodoniumIBA 10/2002 - 04/2002
1	Dopamine (Intropin)FDA LinkGeneric 11/2021
1	Levodopa (L Dopa)FDA LinkGeneric 11/2021
1	Succinate Dehydrogenase (Fumarate Reductase)IBA 01/2021
1	Interleukin-10 (Interleukin 10)IBA 01/2019
1	thiamine triphosphorate (TTP)IBA 01/2018
1	Soluble Guanylyl CyclaseIBA 01/2018
1	Carrier Proteins (Binding Protein)IBA 01/2018
1	IronIBA 01/2018
1	Isradipine (Dynacirc)FDA LinkGeneric 01/2018
1	Erythropoietin FDA Link 01/2018
1	Iron-Regulatory Proteins (Iron-Responsive Element Binding Proteins)IBA 01/2018
1	TristetraprolinIBA 01/2018
1	MicroRNAs (MicroRNA)IBA 09/2015
1	MitoTEMPOIBA 08/2015
1	ChloridesIBA 08/2015
1	CollagenIBA 01/2015
1	Amphibole AsbestosIBA 01/2015
1	Crocidolite Asbestos (Blue Asbestos)IBA 01/2015
1	titanium dioxide (Titania)FDA Link 01/2015
1	Caspase 3 (Caspase-3)IBA 01/2015
1	8-hydroxyguanineIBA 01/2015
1	DNA Glycosylases (DNA Glycosylase)IBA 01/2015
1	Collagen Type I (Type I Collagen)IBA 01/2015
1	AsbestosIBA 01/2015
1	Tamoxifen FDA LinkGeneric 02/2014
1	NAD (NADH)IBA 12/2013
1	SirtuinsIBA 12/2013
1	4- ethoxymethylene- 2- phenyl- 2- oxazoline- 5- one (phOx)IBA 05/2013
1	Cyclin D1IBA 05/2013
1	Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA 04/2013
1	Histone Deacetylase InhibitorsIBA 01/2013
1	Chloroquine (Aralen)FDA LinkGeneric 01/2013
1	abexinostatIBA 01/2013

Therapy/Procedure

3	Therapeutics 01/2018 - 08/2013